Trelli

Your Medicine Cabinet Essentials Redefined

Fancy seeing you here. You're early to the Trelli journey. We're building what natural medicine should have been all along: innovative, clinically effective, fast-acting relief

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Trelli

Trelli

Trustworthy relief

Trelli is built to replace
what’s in your medicine cabinet.

We formulate targeted combinations of enzymes, amino amides, and concentrated botanicals to deliver fast, symptom-specific relief through natural pathways that mirror over-the-counter drug mechanisms.

The Why

Consumer trust in commonly used OTC products has become increasingly challenged. Concerns are emerging around unnecessary ingredients, questionable efficacy, and unintended health impacts.

700+

cold and flu medications contain Phenylephrine, an ingredient the FDA deemed ineffective in 2023. Yet, it remains in most products today.

48+

years have passed since the FDA commissioned a safety review of pain-relieving drugs—a review that remains unexamined to this day

30%

of IBS patients use OTC products that worsen their symptoms instead of providing relief

50%

of acute liver failures in the US are linked to acetaminophen, the most common pain reliever

Not all over-the-counter products are problematic, but there's clearly room for improvement. Trelli offers a new solution.

700+

cold and flu medications contain Phenylephrine, an ingredient the FDA deemed ineffective in 2023. Yet, it remains in most products today.

48+

years have passed since the FDA commissioned a safety review of pain-relieving drugs—a review that remains unexamined to this day

30%

of IBS patients use OTC products that worsen their symptoms instead of providing relief

50%

of acute liver failures in the US are linked to acetaminophen, the most common pain reliever

Our Process

Clear benefits
in a single dose

Our approach is simple and backed by science: every ingredient delivers, without compromising your health.

1

Formulated for
symptom relief

Each ingredient targets a precise symptom profile through evidence-based formulation. We systematically exclude non-essential ingredients that don't contribute to the intended therapeutic outcome, delivering concentrated, clinically-focused formulas with maximum bioactive potential.

2

Clinically studied and validated ingredients

We've analyzed 175+ human clinical trials to build the research foundation behind every formula. We handle the heavy lifting on literature reviews so you don't have to. Our goal is complete transparency about the evidence base and how we validate our therapeutic approaches. We'd love to discuss the science—it's why we're here.

3

Backed by physicians, scientists, dieticians, and medical ethnobotanists

Each ingredient undergoes comprehensive evaluation across safety, toxicology, efficacy, and absorption parameters to establish its complete profile before inclusion in our formulations.

Products

Launching Soon

Introducing our
first three products