Trelli
Trelli
Trelli is built to replace
what’s in your medicine cabinet.
The Why
Consumer trust in commonly used OTC products has become increasingly challenged. Concerns are emerging around unnecessary ingredients, questionable efficacy, and unintended health impacts.
cold and flu medications contain Phenylephrine, an ingredient the FDA deemed ineffective in 2023. Yet, it remains in most products today.
years have passed since the FDA commissioned a safety review of pain-relieving drugs—a review that remains unexamined to this day
of IBS patients use OTC products that worsen their symptoms instead of providing relief
of acute liver failures in the US are linked to acetaminophen, the most common pain reliever
Not all over-the-counter products are problematic, but there's clearly room for improvement. Trelli offers a new solution.
cold and flu medications contain Phenylephrine, an ingredient the FDA deemed ineffective in 2023. Yet, it remains in most products today.
years have passed since the FDA commissioned a safety review of pain-relieving drugs—a review that remains unexamined to this day
of IBS patients use OTC products that worsen their symptoms instead of providing relief
of acute liver failures in the US are linked to acetaminophen, the most common pain reliever
Our Process
Clear benefits
in a single dose
Our approach is simple and backed by science: every ingredient delivers, without compromising your health.

Formulated for
symptom relief
Each ingredient targets a precise symptom profile through evidence-based formulation. We systematically exclude non-essential ingredients that don't contribute to the intended therapeutic outcome, delivering concentrated, clinically-focused formulas with maximum bioactive potential.

Clinically studied and validated ingredients
We've analyzed 175+ human clinical trials to build the research foundation behind every formula. We handle the heavy lifting on literature reviews so you don't have to. Our goal is complete transparency about the evidence base and how we validate our therapeutic approaches. We'd love to discuss the science—it's why we're here.

Backed by physicians, scientists, dieticians, and medical ethnobotanists
Each ingredient undergoes comprehensive evaluation across safety, toxicology, efficacy, and absorption parameters to establish its complete profile before inclusion in our formulations.
Products
Introducing our
first three products

Colomend
Supports digestive comfort and promotes regularity, helping to manage occasional discomfort.

Relivaid
Fast-acting pain support for occasional aches, tension headaches, and menstrual cramps.

Respifix
Supports healthy respiratory function and immune response, easing occasional congestion and seasonal discomfort.